Winterlong
It is big and it is worth praising . ...Winterlong is a dense, graceful, bullying book of great length and much skill; it is a live tale, told in a live voice, by an author of muscle and drive and ambition; it shows the depth of talent available in science fiction. -- John Clute, "The Washington Post" Elizabeth Hand's darkly sensual debut novel took the science fiction and general reading public by storm and now, seven years later, it is available again in a handsome trade paperback edition. Heralded as a considerable stylistic and imaginative accomplishment, as noteworthy in its way as Margaret Atwood's The Handmaid's Tale, by "People" magazine, Winterlong explores the disturbing remains of humanity irrevocably altered by genetic engineering run amok.
Amid the ruins of a once great city, a girl and her beautiful long-lost twin brother are drawn to the seductive voice of a green-eyed boy whose name is Death. Together they must journey through a poisoned garden filled with children who kill and beasts that speak--all the while resisting the evil that compels them to join in a nightmare ritual of blood that will unleash the power of the ancients and signal the end of humanity.
-- From Goodreads